abstract：:Arrhythmogenic right ventricular cardiomyopathy is a primary heart muscle disease characterized by progressive myocardial atrophy of the right ventricle, with transmural fatty or fibrofatty replacement, either segmental or diffuse, accounting for electrical instability at risk of life-threatening ventricular arrhythmi...

journal_title：Herz

authors： Thiene G,Basso C,Calabrese F,Angelini A,Valente M

更新日期：2000-05-01 00:00:00

abstract：:Idiopathic dilated cardiomyopathy is a severe disease of unknown etiology. Accumulating evidence suggests that agonist-like autoantibodies against the beta 1 adrenoceptor in the circulation of dilated cardiomyopathy may play an important role. The aim of this study was to evaluate the effects of the selective beta 1-a...

journal_title：Herz

authors： Matsui S,Persson M,Fu HM,Hayase M,Katsuda S,Teraoka K,Kurihara T,Fu ML

更新日期：2000-05-01 00:00:00

abstract：:In recent years we identified numerous cardiovascular risk factors and had been able to reduce cardiovascular events by a variety of different interventions. There is no question that we can improve the course of coronary artery disease (CAD) in patients with a high-risk profile by modifying these factors. Despite thi...

journal_title：Herz

authors： Schaefer JR,Simon B,Soufi M,Sattler A,Noll B,Herzum M,Maisch B

更新日期：2000-03-01 00:00:00

abstract：:Increased vasoconstriction, activation of platelet vessel wall interaction and invasion of monocytes into the subintima as well as vascular smooth muscle cell proliferation play a fundamental role in the pathogenesis of coronary artery disease. Acute coronary syndromes such as myocardial infarction and unstable angina...

journal_title：Herz

authors： Fichtlscherer S,Zeiher AM

更新日期：1999-11-01 00:00:00

abstract：:The efficacy and tolerance of the standardized hawthorn (crataegus) extract WS 1442 were tested in a multicenter utilization observational study. We monitored 1,011 patients with cardiac insufficiency stage NYHA II, treated with this extract (Crataegutt novo 450, 1 tablet b.i.d.) over a period of 24 weeks. During and ...

journal_title：Herz

authors： Tauchert M,Gildor A,Lipinski J

更新日期：1999-10-01 00:00:00

abstract：:A 55-year-old woman who was admitted to hospital with acute chest pain as a case of emergency suffered from an acute anteroseptal myocardial infarction. Four weeks later coronary angiography revealed a long dissection of the left anterior descending artery (LAD) as well as a significant stenosis of the left main and t...

journal_title：Herz

authors： Lemke P,Schwab M,Urbanyi B,Hellberg K

更新日期：1999-08-01 00:00:00

abstract：:Patients with congenital heart disease have an increased chance to suffer from brady- as well as tachyarrhythmias. The impact of these on quality of life, morbidity and mortality is more often imperative as compared to heart-healthy individuals. The substrate for these may be either congenital or acquired. Improvement...

journal_title：Herz

authors： Hebe J,Krings G,Hansen P,Volkmer M,Ouyang F,Kuck KH

更新日期：1999-06-01 00:00:00

abstract：:Our 19th century predecessors considered the aorta as a source of cardiovascular pain associated with inflammatory aortitis, arterial hypertension, aortic aneurysms, aortic dissection, and aortic valve disease. However, during the 20th century epidemic of coronary artery disease clinicians became concerned with the sy...

journal_title：Herz

authors： Wooley CF,Sparks EH,Boudoulas H

更新日期：1999-04-01 00:00:00

abstract：:In April 1996 the Munich Rehabilitation Center was founded by the Social Security Agency as a "satellite center" of the "Klinik Höhenried for Cardiovascular Diseases", which is located 50 km south of Munich near the lake Starnberg and performs in-patient rehabilitation since 1967. The Munich Rehabilitation Center is e...

journal_title：Herz

authors： Eiber J,Mathes P

更新日期：1999-04-01 00:00:00

abstract：:Numerous angiographic control regression studies have demonstrated that aggressive reduction of plasma cholesterol significantly reduces the incidence of clinical overt cardiovascular complications, but has almost no effect on the angiographically determined luminal diameter of the coronary arteries. These, as well as...

journal_title：Herz

authors： Müller-Wieland D,Faust M,Kotzka J,Krone W

更新日期：1999-02-01 00:00:00

abstract：UNLABELLED:In human tissue sound propagation is not linear resulting in a modification of the ultrasound waves. Therefore the received ultrasound frequencies are not just the transmitted frequencies of the transducer, but contain additional harmonic frequencies. These frequencies were not used by standard echocardiogra...

journal_title：Herz

authors： Becher H,Tiemann K

更新日期：1998-12-01 00:00:00

abstract：:The ideal heart valve prosthesis has not been developed. The today available mechanical and biological prostheses are far from perfect concerning thrombogenesis, mechanical durability and hemodynamic performance. Failure of an implanted valve is possible due to inadequate indication, inadequate surgical technique and ...

journal_title：Herz

authors： Körfer R,Kleikamp G

更新日期：1998-11-01 00:00:00

abstract：:The present data demonstrate clinical feasibility of intracoronary beta brachytherapy and fail to reveal any complications that could be attributed to it. Definitive conclusions regarding safety will have to await longer term evaluation. Proof of efficacy will require strict dose finding evaluation of higher doses tha...

journal_title：Herz

authors： Verin V,Popowski Y

更新日期：1998-09-01 00:00:00

abstract：:Spontaneous rupture of coronary arteries as well as coronary perforation during percutaneous interventions are rare but potentially life-threatening incidents often resulting in emergency surgery. Frequency of acute perforation due to therapeutic catheterization varies according to the devices employed. With conventio...

journal_title：Herz

authors： Elsner M,Zeiher AM

更新日期：1998-08-01 00:00:00

abstract：:Radiofrequency catheter ablation has established as the first line therapy for the curative treatment of patients with accessory pathway. Atrioventricular accessory pathways irrespective of the exact localisation can be successfully ablated in more than 90% of all cases. Severe complications associated with the ablati...

journal_title：Herz

authors： Hindricks G,Kottkamp H,Borggrefe M,Breithardt G

更新日期：1998-06-01 00:00:00

abstract：:In the last years several new data allow a controversial but convincing interpretation of the pathogenesis of atherosclerosis (arteriosclerosis). Atherosclerosis can be apparently the result of ultrachronic persistent infection by Chlamydia pneumoniae and not the result of different risk factors. The main arguments fo...

journal_title：Herz

authors： Stille W,Dittmann R

更新日期：1998-05-01 00:00:00

abstract：:One of the most important problems in clinical cardiology is still unresolved, i.e., the development of a restenosis following coronary balloon angioplasty. Our knowledge about the sequelae of pathophysiologic events occurring during neointima formation is still far from complete (Figure 1) and numerous therapeutic tr...

journal_title：Herz

authors： Darius H,Buerke M,Boissel JP,Grosser T,Veit K,Zacharowski K,Meyer J

更新日期：1997-12-01 00:00:00

abstract：:In addition to its antiarrhythmic and antithrombotic effects magnesium is said to have a beneficial effect in patients with acute myocardial infarction. Magnesium can protect myocardial tissue after coronary occlusion and reduces infarct size in experimental models of ischaemia and reperfusion, though the given doses ...

journal_title：Herz

authors： Thämer V,Grunert S,Bier F,Schlack W

更新日期：1997-06-01 00:00:00

abstract：:We report the case of a patient with both a left bundle branch block-preexcited tachycardia using a Mahaim bundle and a tachycardia exhibiting a left bundle branch pattern without preexcited complexes related to an AV nodal reentrant tachycardia. Successful ablation of the nodoventricular tract was obtained in the pos...

journal_title：Herz

authors： Beurrier D,Brembilla-Perrot B,Bragard MF

更新日期：1996-10-01 00:00:00

abstract：:Formerly the term alcoholism has been defined only by alcohol-related conditions. About 20 years ago a WHO committee recommended to differentiate between alcohol abuse and alcohol dependence. The new classifications and manuals followed this proposal: Criteria for alcohol abuse are still alcohol sequelae whereas alcoh...

journal_title：Herz

authors： Feuerlein W

更新日期：1996-08-01 00:00:00

abstract：:Between 1975 and 1991, 5 patients were operated for traumatic tricuspid insufficiency. The patients, all male, with the age at surgery of 15 to 61 years (mean 39 years), suffered previous nonpenetrating trauma to the chest 0.1 to 23 years (mean 13.2 years) earlier. Symptoms were known for 0 to 18 years (mean 10.5 year...

journal_title：Herz

authors： Holper K,Hähnel C,Augustin N,Meisner H

更新日期：1996-06-01 00:00:00

abstract：:Nitrates have been periodically controversial since their introduction in 1867 as a treatment for angina pectoris. The goal of this synopsis is to delineate the special and unchanged high ranking of nitrates in the treatment of angina pectoris with particular consideration to the dosage and dosage intervals. The anti-...

journal_title：Herz

authors： Silber S

更新日期：1996-06-01 00:00:00

abstract：:The success of percutaneous transluminal coronary angioplasty (PTCA) is limited by vessel dissection with subsequent vessel occlusion in the acute phase and by restenosis chronically. The implantation of intracoronary stents allows to manage acute complications more efficiently and reduce restenosis rate. Anticoagulat...

journal_title：Herz

authors： Bode C,Nordt TK,Kübler W

更新日期：1996-02-01 00:00:00

abstract：:Based on the epidemiologic data of the Framingham heart study, arterial hypertension and coronary artery disease are the most frequent etiologic factors for the development of heart failure. In the pressure overloaded heart, hypertrophic growth of the myocardium includes the enlargement of cardiac myocytes stimulated ...

journal_title：Herz

authors： Funck RC,Wilke A,Rupp H,Maisch B,Brilla CG

更新日期：1995-10-01 00:00:00

abstract：:In this investigation, we studied the feasibility of 3D-reconstruction from 2D cross-sectional intracoronary ultrasound images. A computer-aided, automated 3D-reconstruction was used to generate cylindrical and sagittal format of vessels in vitro (n = 9) and in vivo (n = 48). Ultrasound 2D-images were acquired with a ...

journal_title：Herz

authors： Ge J,Koch L,Roth T,Görge G,Kearney P,Haude M,Baumgart D,von Birgelen C,Brennecke R,Meyer J

更新日期：1995-08-01 00:00:00

abstract：:During recent years, experimental data have collected convincing evidence for the fatal interaction of myocardial ischemia, ventricular tachyarrhythmias, and sudden cardiac death. In the clinical setting, data reporting on the daily relevance of such a fatal interaction lacked until recently. However, there is now inc...

journal_title：Herz

authors： Zehender M,Faber T,Meinertz T,Just H

更新日期：1995-06-01 00:00:00

abstract：:Our own previous studies of the composition of the extracellular matrix of human failing hearts showed that collagen VI seems to play a major role in the origin of cardiac fibrosis. Therefore, collagen VI was investigated in more detail in tissue samples taken from clinically normal left ventricle and from myocardium ...

journal_title：Herz

authors： Mollnau H,Münkel B,Schaper J

更新日期：1995-04-01 00:00:00

abstract：:In the past decade, thrombolytic therapy has become standard treatment of acute myocardial infarction. When the importance of thrombosis in the pathogenesis of acute infarction was fully recognised, several plasminogen activators were developed, streptokinase, urokinase, recombinant tissue-type plasminogen activator (...

journal_title：Herz

authors： Rutsch W,Schmutzler H

更新日期：1994-12-01 00:00:00

abstract：:Despite all advances in the diagnostic and therapy of cardiovascular diseases the mortality from malignant ventricular tachyarrhythmias is still a major health problem. In addition to established therapeutic strategies in the prevention of sudden cardiac death such as antiarrhythmic drug treatment, catheter ablation o...

journal_title：Herz

authors： Neuzner J,Pitschner HF,Schlepper M

更新日期：1994-10-01 00:00:00

abstract：:We report the case of a 28-year old asthmatic female patient, who developed an acute heart failure beginning with diarrhea, fever, and dyspnea 5 weeks after delivery. After improvement of all vital functions and dismissal from hospital care unit a marked blood hypereosinophilia, left ventricular congestive heart failu...

journal_title：Herz

authors： Gehrke D,Herzum M,Schönian U,Klein HH,Drude L,Mennel HD,Maisch B

更新日期：1994-06-01 00:00:00

abstract：:Modern therapeutic options in ischemic coronary disease such as thrombolysis, coronary angioplasty, new emerging strategies in treating heart failure and secondary prevention have resulted in decreasing cardiac mortality over the last ten years. In the era of interventional cardiology a new focus of clinical interest ...

journal_title：Herz

authors： Nienaber CA,Meinertz T

更新日期：1994-02-01 00:00:00

abstract：:In the clinical management of patients with valvular heart disease, transthoracic echocardiography (TTE) combined with Doppler has become the central diagnostic tool during the past decades. The development of transesophageal echocardiography (TEE) has led to an improved image quality especially of structures distant ...

journal_title：Herz

authors： Niedermeyer J,Daniel WG

更新日期：1993-12-01 00:00:00

abstract：:The incidence of coronary heart disease and myocardial infarction fell gradually during the seventies. Reasons for this decline are not well understood. Speculations include changes of life style and health care. However, cardiovascular disease is still the leader of mortality in Western developed countries. Mortality...

journal_title：Herz

authors： Ertl G,Gaudron P,Eilles C,Kochsiek K

更新日期：1993-12-01 00:00:00

abstract：:The genetic information for the development of an organism is stored and inherited by deoxyribonucleic acid (DNA). In higher organisms the DNA is located within the cell nucleus. DNA has the structure of a double helix and contains a specific sequence of four types of nucleotides that are specified by the bases adenin...

journal_title：Herz

authors： Marian AJ,Roberts R

更新日期：1993-08-01 00:00:00

abstract：:Disorders of the autonomic nervous control mechanisms of heart rate and vascular tone may cause syncope. Notably these are carotid sinus and vasovagal syndromes. Knowledge of their aetiology is limited. Each presents cardioinhibition and vasodepression. Pacing offers benefit in cardioinhibition and the mode required i...

journal_title：Herz

authors： Sutton R

更新日期：1993-06-01 00:00:00

abstract：:For more than two centuries digitalis has been used in the treatment of cardiac disease. Despite this long clinical experience with the drug, controversy still exists as to its clinical effect and impact on survival, especially in patients after myocardial infarction. In the last decade a number of studies have addres...

journal_title：Herz

authors： Mølstad P

更新日期：1993-04-01 00:00:00

abstract：:The decision to anticoagulate patients with atrial fibrillation (AF) involves weighting the risk of an embolic event without therapy versus the risk of a hemorrhagic event on therapy. Improved methods of monitoring anticoagulation with the International Normalized Ratio (INR), and recent evidence of the efficacy and s...

journal_title：Herz

authors： Atwood JE,Albers GW

更新日期：1993-02-01 00:00:00

abstract：:Endothelial cells synthesize and metabolize vasoactive substances which are involved in the regulation of vascular tone. Among these factors, the endothelium-derived nitric oxide (NO) appears to be of major importance. Many studies observed an impairment of the generation, release, or the diffusion of endothelial NO a...

journal_title：Herz

authors： Bossaller C,Reither K,Hehlert-Friedrich C,Auch-Schwelk W,Graf K,Gräfe M,Fleck E

更新日期：1992-10-01 00:00:00

abstract：:Numerous clinical and experimental studies have suggested that adequate pulmonary blood flow and normal central venous pressure may be maintained without significant contribution of right ventricular function. These data induced experimental and clinical research in the quest for complete bypass of the right heart. Mo...

journal_title：Herz

authors： Robicsek F

更新日期：1992-08-01 00:00:00

abstract：:With intravenous thrombolysis mortality of acute myocardial infarction can be significantly reduced, not only in the first hours after the onset of symptoms, but also up to 24 hours. The open infarct related coronary artery is important concerning long-term clinical outcome. If thrombolysis can be administered within ...

journal_title：Herz

authors： Rutsch W

更新日期：1992-02-01 00:00:00